Divergent total synthesis of taiwaniaquinones A and F and taiwaniaquinols B and D.
نویسندگان
چکیده
A divergent approach was developed toward the total synthesis of taiwaniaquinoids. An advanced intermediate 5a with trans A/B ring junction was concisely assembled by employing a Bi(OTf)3-catalyzed cationic cyclization and a Wolff-type ring contraction as key steps. This common intermediate was readily converted to racemic taiwaniaquinones A and F and taiwaniaquinols B and D, respectively.
منابع مشابه
Enantioselective total synthesis of cytotoxic taiwaniaquinones A and F.
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عنوان ژورنال:
- Organic letters
دوره 15 8 شماره
صفحات -
تاریخ انتشار 2013